Interferon-γ Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is characterized by the proliferation of immature myeloid lineage blasts. Due to its heterogeneity and to the high rate of acquired drug resistance and relapse, new treatment strategies are needed. Here, we demonstrate that IFNγ promotes AML blasts to act as effector cel...

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Библиографические подробности
Опубликовано в: :J Biol Chem
Главные авторы: Fatehchand, Kavin, McMichael, Elizabeth L., Reader, Brenda F., Fang, Huiqing, Santhanam, Ramasamy, Gautam, Shalini, Elavazhagan, Saranya, Mehta, Payal, Buteyn, Nathaniel J., Merchand-Reyes, Giovanna, Vasu, Sumithira, Mo, Xiaokui, Benson, Don M., Blachly, James S., Carson, William E., Byrd, John C., Butchar, Jonathan P., Tridandapani, Susheela
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2016
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207262/
https://ncbi.nlm.nih.gov/pubmed/27780867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753145
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