Interferon-γ Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) is characterized by the proliferation of immature myeloid lineage blasts. Due to its heterogeneity and to the high rate of acquired drug resistance and relapse, new treatment strategies are needed. Here, we demonstrate that IFNγ promotes AML blasts to act as effector cel...

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Bibliografische gegevens
Gepubliceerd in:J Biol Chem
Hoofdauteurs: Fatehchand, Kavin, McMichael, Elizabeth L., Reader, Brenda F., Fang, Huiqing, Santhanam, Ramasamy, Gautam, Shalini, Elavazhagan, Saranya, Mehta, Payal, Buteyn, Nathaniel J., Merchand-Reyes, Giovanna, Vasu, Sumithira, Mo, Xiaokui, Benson, Don M., Blachly, James S., Carson, William E., Byrd, John C., Butchar, Jonathan P., Tridandapani, Susheela
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Biochemistry and Molecular Biology 2016
Onderwerpen:
Immunology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207262/
https://ncbi.nlm.nih.gov/pubmed/27780867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.753145
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