Molecular Determinants of Scaffold-induced Linear Ubiquitinylation of B Cell Lymphoma/Leukemia 10 (Bcl10) during T Cell Receptor and Oncogenic Caspase Recruitment Domain-containing Protein 11 (CARD11) Signaling

The activation of NF-κB downstream of T cell receptor (TCR) engagement is a key signaling step required for normal lymphocyte function during the adaptive immune response. During TCR signaling, the adaptor protein Bcl10 is inducibly recruited to the CARD11 scaffold protein as part of a multicomponen...

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Publicado en:J Biol Chem
Autores principales: Yang, Yong-Kang, Yang, Chao, Chan, Waipan, Wang, Zhaoquan, Deibel, Katelynn E., Pomerantz, Joel L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2016
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207066/
https://ncbi.nlm.nih.gov/pubmed/27777308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.754028
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