Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

Chimeric antigen receptor T (CAR-T) cells have demonstrated promising results against hematological malignancies but have encountered significant challenges in translation to solid tumors. To overcome these hurdles, we have developed a switchable CAR-T cell platform in which the activity of the engi...

詳細記述

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書誌詳細
出版年:Angew Chem Int Ed Engl
主要な著者: Cao, Yu, Rodgers, David T., Du, Juanjuan, Ahmad, Insha, Hampton, Eric N., Ma, Jennifer S. Y., Mazagova, Magdalena, Choi, Sei-hyun, Yun, Hwa Young, Xiao, Han, Yang, Pengyu, Luo, Xiaozhou, Lim, Reyna K. V., Pugh, Holly M., Wang, Feng, Kazane, Stephanie A., Wright, Timothy M., Kim, Chan Hyuk, Schultz, Peter G., Young, Travis S.
フォーマット: Artigo
言語:Inglês
出版事項: 2016
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207029/
https://ncbi.nlm.nih.gov/pubmed/27145250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201601902
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