Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1

OBJECTIVE: To assess the efficacy of lovastatin on visuospatial learning and attention for treating cognitive and behavioral deficits in children with neurofibromatosis type 1 (NF1). METHODS: A multicenter, international, randomized, double-blind, placebo-controlled trial was conducted between July...

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Vydáno v:Neurology
Hlavní autoři: Payne, Jonathan M., Barton, Belinda, Ullrich, Nicole J., Cantor, Alan, Hearps, Stephen J.C., Cutter, Gary, Rosser, Tena, Walsh, Karin S., Gioia, Gerard A., Wolters, Pamela L., Tonsgard, James, Schorry, Elizabeth, Viskochil, David, Klesse, Laura, Fisher, Michael, Gutmann, David H., Silva, Alcino J., Hunter, Scott J., Rey-Casserly, Celiane, Cantor, Nancy L., Byars, Anna W., Stavinoha, Peter L., Ackerson, Joseph D., Armstrong, Carol L., Isenberg, Jill, O'Neil, Sharon H., Packer, Roger J., Korf, Bruce, Acosta, Maria T., North, Kathryn N.
Médium: Artigo
Jazyk:Inglês
Vydáno: Lippincott Williams & Wilkins 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207004/
https://ncbi.nlm.nih.gov/pubmed/27956565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003435
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