Randomized placebo-controlled study of lovastatin in children with neurofibromatosis type 1

OBJECTIVE: To assess the efficacy of lovastatin on visuospatial learning and attention for treating cognitive and behavioral deficits in children with neurofibromatosis type 1 (NF1). METHODS: A multicenter, international, randomized, double-blind, placebo-controlled trial was conducted between July...

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Detalhes bibliográficos
Publicado no:Neurology
Main Authors: Payne, Jonathan M., Barton, Belinda, Ullrich, Nicole J., Cantor, Alan, Hearps, Stephen J.C., Cutter, Gary, Rosser, Tena, Walsh, Karin S., Gioia, Gerard A., Wolters, Pamela L., Tonsgard, James, Schorry, Elizabeth, Viskochil, David, Klesse, Laura, Fisher, Michael, Gutmann, David H., Silva, Alcino J., Hunter, Scott J., Rey-Casserly, Celiane, Cantor, Nancy L., Byars, Anna W., Stavinoha, Peter L., Ackerson, Joseph D., Armstrong, Carol L., Isenberg, Jill, O'Neil, Sharon H., Packer, Roger J., Korf, Bruce, Acosta, Maria T., North, Kathryn N.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5207004/
https://ncbi.nlm.nih.gov/pubmed/27956565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0000000000003435
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