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Mocetinostat (MGCD0103): a review of an isotype-specific histone deacetylase inhibitor

INTRODUCTION: HDAC inhibitors (HDACIs) have the potential to restore gene expression and display antitumor effects in vitro. As single agents, HDACIs have clinical activity in lymphoma. In myeloid leukemias, combinations of DNA methylation inhibitors and HDACIs are promising. Other combinations are...

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Bibliografski detalji
Izdano u:Expert Opin Investig Drugs
Glavni autori: Boumber, Yanis, Younes, Anas, Garcia-Manero, Guillermo
Format: Artigo
Jezik:Inglês
Izdano: 2011
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206967/
https://ncbi.nlm.nih.gov/pubmed/21554162
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/13543784.2011.577737
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