ロード中...
Biasing genome-editing events toward precise length deletions with an RNA-guided TevCas9 dual nuclease
The CRISPR/Cas9 nuclease is commonly used to make gene knockouts. The blunt DNA ends generated by cleavage can be efficiently ligated by the classical nonhomologous end-joining repair pathway (c-NHEJ), regenerating the target site. This repair creates a cycle of cleavage, ligation, and target site r...
保存先:
| 出版年: | Proc Natl Acad Sci U S A |
|---|---|
| 主要な著者: | , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2016
|
| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5206545/ https://ncbi.nlm.nih.gov/pubmed/27956611 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1616343114 |
| タグ: |
タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!
|