Computational design of a homotrimeric metalloprotein with a trisbipyridyl core

Metal-chelating heteroaryl small molecules have found widespread use as building blocks for coordination-driven, self-assembling nanostructures. The metal-chelating noncanonical amino acid (2,2′-bipyridin-5yl)alanine (Bpy-ala) could, in principle, be used to nucleate specific metalloprotein assembli...

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Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Mills, Jeremy H., Sheffler, William, Ener, Maraia E., Almhjell, Patrick J., Oberdorfer, Gustav, Pereira, José Henrique, Parmeggiani, Fabio, Sankaran, Banumathi, Zwart, Peter H., Baker, David
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2016
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206526/
https://ncbi.nlm.nih.gov/pubmed/27940918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1600188113
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