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Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins

Chlorinated phospholipids are formed by the reaction of hypochlorous acid (HOCl), generated by the enzyme myeloperoxidase under inflammatory conditions, and the unsaturated fatty acyl residues or the head group. In the first case the generated chlorohydrins are both proinflammatory and cytotoxic, th...

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Détails bibliographiques
Publié dans:Oxid Med Cell Longev
Auteurs principaux: Schröter, Jenny, Schiller, Jürgen
Format: Artigo
Langue:Inglês
Publié: Hindawi Publishing Corporation 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206476/
https://ncbi.nlm.nih.gov/pubmed/28090245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8386362
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