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Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins

Chlorinated phospholipids are formed by the reaction of hypochlorous acid (HOCl), generated by the enzyme myeloperoxidase under inflammatory conditions, and the unsaturated fatty acyl residues or the head group. In the first case the generated chlorohydrins are both proinflammatory and cytotoxic, th...

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Pubblicato in:Oxid Med Cell Longev
Autori principali: Schröter, Jenny, Schiller, Jürgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi Publishing Corporation 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206476/
https://ncbi.nlm.nih.gov/pubmed/28090245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8386362
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