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Chlorinated Phospholipids and Fatty Acids: (Patho)physiological Relevance, Potential Toxicity, and Analysis of Lipid Chlorohydrins

Chlorinated phospholipids are formed by the reaction of hypochlorous acid (HOCl), generated by the enzyme myeloperoxidase under inflammatory conditions, and the unsaturated fatty acyl residues or the head group. In the first case the generated chlorohydrins are both proinflammatory and cytotoxic, th...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Schröter, Jenny, Schiller, Jürgen
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5206476/
https://ncbi.nlm.nih.gov/pubmed/28090245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/8386362
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