The number of positively charged amino acids in the basic domain of Tat is critical for trans-activation and complex formation with TAR RNA.

Podobné jednotky

• Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure.
  Autor: Delling, U, a další
  Vydáno: (1992)
• Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein.
  Autor: Sumner-Smith, M, a další
  Vydáno: (1991)
• Rotational symmetry in ribonucleotide strand requirements for binding of HIV-1 Tat protein to TAR RNA.
  Autor: Barnett, R W, a další
  Vydáno: (1993)
• The basic RNA-binding domain of HIV-2 Tat contributes to preferential trans-activation of a TAR2-containing LTR.
  Autor: Chang, Y N, a další
  Vydáno: (1992)
• Structural requirements for trans activation of human immunodeficiency virus type 1 long terminal repeat-directed gene expression by tat: importance of base pairing, loop sequence, and bulges in the tat-responsive sequence.
  Autor: Roy, S, a další
  Vydáno: (1990)