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Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein.

The human immunodeficiency virus type 1 Tat protein binds to an RNA stem-loop structure called TAR which is present at the 5' end of all human immunodeficiency virus type 1 transcripts. This binding is centered on a bulge within the stem of TAR and is an essential step in the trans-activation p...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Sumner-Smith, M, Roy, S, Barnett, R, Reid, L S, Kuperman, R, Delling, U, Sonenberg, N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248997/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1895380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5196-5202.1991
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