Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure.

Interaction between the human immunodeficiency virus type 1 (HIV-1) trans-activator Tat and its cis-acting responsive RNA element TAR is necessary for activation of HIV-1 gene expression. We investigated the hypothesis that the essential uridine residue at position 23 in the bulge of TAR RNA is invo...

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Détails bibliographiques
Auteurs principaux: Delling, U, Reid, L S, Barnett, R W, Ma, M Y, Climie, S, Sumner-Smith, M, Sonenberg, N
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC241061/
https://ncbi.nlm.nih.gov/pubmed/1560535
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