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Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure.

Interaction between the human immunodeficiency virus type 1 (HIV-1) trans-activator Tat and its cis-acting responsive RNA element TAR is necessary for activation of HIV-1 gene expression. We investigated the hypothesis that the essential uridine residue at position 23 in the bulge of TAR RNA is invo...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Delling, U, Reid, L S, Barnett, R W, Ma, M Y, Climie, S, Sumner-Smith, M, Sonenberg, N
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1992
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241061/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1560535/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3018-3025.1992
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