Conserved nucleotides in the TAR RNA stem of human immunodeficiency virus type 1 are critical for Tat binding and trans activation: model for TAR RNA tertiary structure.

Interaction between the human immunodeficiency virus type 1 (HIV-1) trans-activator Tat and its cis-acting responsive RNA element TAR is necessary for activation of HIV-1 gene expression. We investigated the hypothesis that the essential uridine residue at position 23 in the bulge of TAR RNA is invo...

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Publié dans:	J Virol
Auteurs principaux:	Delling, U, Reid, L S, Barnett, R W, Ma, M Y, Climie, S, Sumner-Smith, M, Sonenberg, N
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1992
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC241061/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1560535/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.66.5.3018-3025.1992
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