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Critical chemical features in trans-acting-responsive RNA are required for interaction with human immunodeficiency virus type 1 Tat protein.

The human immunodeficiency virus type 1 Tat protein binds to an RNA stem-loop structure called TAR which is present at the 5' end of all human immunodeficiency virus type 1 transcripts. This binding is centered on a bulge within the stem of TAR and is an essential step in the trans-activation p...

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Autors principals: Sumner-Smith, M, Roy, S, Barnett, R, Reid, L S, Kuperman, R, Delling, U, Sonenberg, N
Format: Artigo
Idioma:Inglês
Publicat: 1991
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC248997/
https://ncbi.nlm.nih.gov/pubmed/1895380
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