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The Transactivation Domains of the p53 Protein
The p53 tumor suppressor is a transcriptional activator, with discrete domains that participate in sequence-specific DNA binding, tetramerization, and transcriptional activation. Mutagenesis and reporter studies have delineated two distinct activation domains (TADs) and specific hydrophobic residues...
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| Pubblicato in: | Cold Spring Harb Perspect Med |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Cold Spring Harbor Laboratory Press
2017
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5204331/ https://ncbi.nlm.nih.gov/pubmed/27864306 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a026047 |
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