Concentrations of Pro-Inflammatory Cytokines Are Not Associated with Senescence Marker p16(INK4a) or Predictive of Intracellular Emtricitabine/Tenofovir Metabolite and Endogenous Nucleotide Exposures in Adults with HIV Infection

OBJECTIVES: As the HIV-infected population ages, the role of cellular senescence and inflammation on co-morbid conditions and pharmacotherapy is increasingly of interest. p16(INK4a) expression, a marker for aging and senescence in T-cells, is associated with lower intracellular concentrations of end...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:PLoS One
Κύριοι συγγραφείς: Maas, Brian M., Francis, Owen, Mollan, Katie R., Lee, Cynthia, Cottrell, Mackenzie L., Prince, Heather M. A., Sykes, Craig, Trezza, Christine, Torrice, Chad, White, Nicole, Malone, Stephanie, Hudgens, Michael G., Sharpless, Norman E., Dumond, Julie B.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: Public Library of Science 2016
Θέματα:
Research Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201235/
https://ncbi.nlm.nih.gov/pubmed/28036343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0168709
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