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Fast and selective labeling of N-terminal cysteines at neutral pH via thiazolidino boronate formation

Facile labeling of proteins of interest is highly desirable in proteomic research as well as in the development of protein therapeutics. Herein we report a novel method that allows for fast and selective labeling of proteins with an N-terminal cysteine. Although N-terminal cysteines are well known t...

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Publicado en:Chem Sci
Autores principales: Bandyopadhyay, Anupam, Cambray, Samantha, Gao, Jianmin
Formato: Artigo
Lenguaje:Inglês
Publicado: Royal Society of Chemistry 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201210/
https://ncbi.nlm.nih.gov/pubmed/28044097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00172f
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