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Fast and selective labeling of N-terminal cysteines at neutral pH via thiazolidino boronate formation

Facile labeling of proteins of interest is highly desirable in proteomic research as well as in the development of protein therapeutics. Herein we report a novel method that allows for fast and selective labeling of proteins with an N-terminal cysteine. Although N-terminal cysteines are well known t...

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Vydáno v:Chem Sci
Hlavní autoři: Bandyopadhyay, Anupam, Cambray, Samantha, Gao, Jianmin
Médium: Artigo
Jazyk:Inglês
Vydáno: Royal Society of Chemistry 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201210/
https://ncbi.nlm.nih.gov/pubmed/28044097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00172f
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