A carregar...

Iminoboronate Formation Leads to Fast and Reversible Conjugation Chemistry of α-Nucleophiles at Neutral pH

Bioorthogonal reactions that are fast and reversible under physiologic conditions are in high demand for biological applications. Herein, we show that an ortho boronic acid substituent makes aryl ketones to rapidly conjugate with α-nucleophiles at neutral pH. Specifically, 2-acetylphenylboronic acid...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Bandyopadhyay, Anupam, Gao, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4699557/
https://ncbi.nlm.nih.gov/pubmed/26311464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201502077
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!