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Iminoboronate-based peptide cyclization that responds to pH, oxidation, and small molecule modulators
As a rich source of therapeutic agents, peptide natural products usually adopt a cyclic or multicyclic scaffold that minimizes structural flexibility to favor target binding. Inspired by nature, chemists have been interested in developing synthetic cyclic and multicyclic peptides that serve as biolo...
Tallennettuna:
| Julkaisussa: | J Am Chem Soc |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4842000/ https://ncbi.nlm.nih.gov/pubmed/26859098 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b12301 |
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