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Fast and selective labeling of N-terminal cysteines at neutral pH via thiazolidino boronate formation

Facile labeling of proteins of interest is highly desirable in proteomic research as well as in the development of protein therapeutics. Herein we report a novel method that allows for fast and selective labeling of proteins with an N-terminal cysteine. Although N-terminal cysteines are well known t...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Bandyopadhyay, Anupam, Cambray, Samantha, Gao, Jianmin
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201210/
https://ncbi.nlm.nih.gov/pubmed/28044097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc00172f
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