SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation

Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, neurodegenerative diseases and progeria. Here, we show that SIRT2 depletion or overexpression causes nuclear envelope reasse...

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Publicado en:J Cell Sci
Autores principales: Kaufmann, Tanja, Kukolj, Eva, Brachner, Andreas, Beltzung, Etienne, Bruno, Melania, Kostrhon, Sebastian, Opravil, Susanne, Hudecz, Otto, Mechtler, Karl, Warren, Graham, Slade, Dea
Formato: Artigo
Lenguaje:Inglês
Publicado: The Company of Biologists Ltd 2016
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201015/
https://ncbi.nlm.nih.gov/pubmed/27875273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192633
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