SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation

Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, neurodegenerative diseases and progeria. Here, we show that SIRT2 depletion or overexpression causes nuclear envelope reasse...

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Publicat a:J Cell Sci
Autors principals: Kaufmann, Tanja, Kukolj, Eva, Brachner, Andreas, Beltzung, Etienne, Bruno, Melania, Kostrhon, Sebastian, Opravil, Susanne, Hudecz, Otto, Mechtler, Karl, Warren, Graham, Slade, Dea
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists Ltd 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201015/
https://ncbi.nlm.nih.gov/pubmed/27875273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192633
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