SIRT2 regulates nuclear envelope reassembly through ANKLE2 deacetylation

Sirtuin 2 (SIRT2) is an NAD-dependent deacetylase known to regulate microtubule dynamics and cell cycle progression. SIRT2 has also been implicated in the pathology of cancer, neurodegenerative diseases and progeria. Here, we show that SIRT2 depletion or overexpression causes nuclear envelope reasse...

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Bibliografische gegevens
Gepubliceerd in:J Cell Sci
Hoofdauteurs: Kaufmann, Tanja, Kukolj, Eva, Brachner, Andreas, Beltzung, Etienne, Bruno, Melania, Kostrhon, Sebastian, Opravil, Susanne, Hudecz, Otto, Mechtler, Karl, Warren, Graham, Slade, Dea
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists Ltd 2016
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5201015/
https://ncbi.nlm.nih.gov/pubmed/27875273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.192633
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