Helicobacter pylori VacA, acting through receptor protein tyrosine phosphatase α, is crucial for CagA phosphorylation in human duodenum carcinoma cell line AZ-521

Helicobacter pylori, a major cause of gastroduodenal diseases, produces vacuolating cytotoxin (VacA) and cytotoxin-associated gene A (CagA), which seem to be involved in virulence. VacA exhibits pleiotropic actions in gastroduodenal disorders via its specific receptors. Recently, we found that VacA...

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Udgivet i:Dis Model Mech
Main Authors: Nakano, Masayuki, Yahiro, Kinnosuke, Yamasaki, Eiki, Kurazono, Hisao, Akada, Junko, Yamaoka, Yoshio, Niidome, Takuro, Hatakeyama, Masanori, Suzuki, Hidekazu, Yamamoto, Taro, Moss, Joel, Isomoto, Hajime, Hirayama, Toshiya
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5200893/
https://ncbi.nlm.nih.gov/pubmed/27935824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.025361
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