Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long‐term intermittent hypoxia

KEY POINTS: The effects of short‐term (ST; 10 days) and long‐term (LT; 30 days) intermittent hypoxia (IH) on blood pressure (BP), breathing and carotid body (CB) chemosensory reflex were examined in adult rats. ST‐ and LT‐IH treated rats exhibited hypertension, irregular breathing with apnoea and au...

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Publicat a:J Physiol
Autors principals: Nanduri, Jayasri, Peng, Ying‐Jie, Wang, Ning, Khan, Shakil A., Semenza, Gregg L., Kumar, Ganesh K., Prabhakar, Nanduri R.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Symposium section reviews: Targeting autonomic imbalance in pathophysiology: is the carotid body the new nirvana?
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199741/
https://ncbi.nlm.nih.gov/pubmed/27506145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272346
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