Epigenetic regulation of redox state mediates persistent cardiorespiratory abnormalities after long‐term intermittent hypoxia

KEY POINTS: The effects of short‐term (ST; 10 days) and long‐term (LT; 30 days) intermittent hypoxia (IH) on blood pressure (BP), breathing and carotid body (CB) chemosensory reflex were examined in adult rats. ST‐ and LT‐IH treated rats exhibited hypertension, irregular breathing with apnoea and au...

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Publicado en:J Physiol
Main Authors: Nanduri, Jayasri, Peng, Ying‐Jie, Wang, Ning, Khan, Shakil A., Semenza, Gregg L., Kumar, Ganesh K., Prabhakar, Nanduri R.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Symposium section reviews: Targeting autonomic imbalance in pathophysiology: is the carotid body the new nirvana?
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5199741/
https://ncbi.nlm.nih.gov/pubmed/27506145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP272346
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