T-Bet Enhances Regulatory T Cell Fitness and Directs Control of Th1 Responses in Crescentic GN

Th1 cells are central pathogenic mediators of crescentic GN (cGN). Mechanisms responsible for Th1 cell downregulation, however, remain widely unknown. Recently, it was proposed that activation of the Th1–characteristic transcription factor T-bet optimizes Foxp3(+) regulatory T (Treg) cells to counte...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Am Soc Nephrol
Egile Nagusiak: Nosko, Anna, Kluger, Malte A., Diefenhardt, Paul, Melderis, Simon, Wegscheid, Claudia, Tiegs, Gisa, Stahl, Rolf A.K., Panzer, Ulf, Steinmetz, Oliver M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society of Nephrology 2017
Gaiak:
Basic Research
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5198267/
https://ncbi.nlm.nih.gov/pubmed/27297951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2015070820
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