Limited Tumor Tissue Drug Penetration Contributes to Primary Resistance against Angiogenesis Inhibitors

Resistance mechanisms against antiangiogenic drugs are unclear. Here, we correlated the antitumor and antivascular properties of five different antiangiogenic receptor tyrosine kinase inhibitors (RTKIs) (motesanib, pazopanib, sorafenib, sunitinib, vatalanib) with their intratumoral distribution data...

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Detaylı Bibliyografya
Yayımlandı:Theranostics
Asıl Yazarlar: Torok, Szilvia, Rezeli, Melinda, Kelemen, Olga, Vegvari, Akos, Watanabe, Kenichi, Sugihara, Yutaka, Tisza, Anna, Marton, Timea, Kovacs, Ildiko, Tovari, Jozsef, Laszlo, Viktoria, Helbich, Thomas H., Hegedus, Balazs, Klikovits, Thomas, Hoda, Mir Alireza, Klepetko, Walter, Paku, Sandor, Marko-Varga, Gyorgy, Dome, Balazs
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Ivyspring International Publisher 2017
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5197073/
https://ncbi.nlm.nih.gov/pubmed/28042343
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7150/thno.16767
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