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Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.

Myogenin is a muscle-specific nuclear factor that acts as a genetic switch to activate myogenesis. Myogenin, MyoD, and a growing number of proteins implicated in transcriptional control share sequence homology within a basic region and an adjacent helix-loop-helix motif. Here we identify by site-dir...

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Detalhes bibliográficos
Main Authors: Brennan, T J, Chakraborty, T, Olson, E N
Formato: Artigo
Idioma:Inglês
Publicado em: 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC51940/
https://ncbi.nlm.nih.gov/pubmed/1648228
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