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Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.

Myogenin is a muscle-specific nuclear factor that acts as a genetic switch to activate myogenesis. Myogenin, MyoD, and a growing number of proteins implicated in transcriptional control share sequence homology within a basic region and an adjacent helix-loop-helix motif. Here we identify by site-dir...

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Bibliografiske detaljer
Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Brennan, T J, Chakraborty, T, Olson, E N
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 1991
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51940/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648228/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5675
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