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Domains outside of the DNA-binding domain impart target gene specificity to myogenin and MRF4.

Myogenin and MRF4 belong to the MyoD family of muscle-specific transcription factors, which can activate myogenesis when introduced into nonmyogenic cells. These proteins share homology within a basic-helix-loop-helix motif that mediates DNA binding and dimerization, but they are divergent in their...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Chakraborty, T, Olson, E N
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 1991
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361787/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658626/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.12.6103-6108.1991
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