Domains outside of the DNA-binding domain impart target gene specificity to myogenin and MRF4.
Myogenin and MRF4 belong to the MyoD family of muscle-specific transcription factors, which can activate myogenesis when introduced into nonmyogenic cells. These proteins share homology within a basic-helix-loop-helix motif that mediates DNA binding and dimerization, but they are divergent in their...
Uloženo v:
| Vydáno v: | Mol Cell Biol |
|---|---|
| Hlavní autoři: | , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Taylor & Francis
1991
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC361787/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1658626/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.11.12.6103-6108.1991 |
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