Mutagenesis of the myogenin basic region identifies an ancient protein motif critical for activation of myogenesis.
Myogenin is a muscle-specific nuclear factor that acts as a genetic switch to activate myogenesis. Myogenin, MyoD, and a growing number of proteins implicated in transcriptional control share sequence homology within a basic region and an adjacent helix-loop-helix motif. Here we identify by site-dir...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC51940/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1648228/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.13.5675 |
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