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Comparative In Vivo Efficacies of Tedizolid in Neutropenic versus Immunocompetent Murine Streptococcus pneumoniae Lung Infection Models

Given that tedizolid exhibits substantial lung penetration, we hypothesize that it could achieve good efficacy against Streptococcus pneumoniae lung infections. We evaluated the pharmacodynamics of tedizolid for treatment of S. pneumoniae lung infections and compared the efficacies of tedizolid huma...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Abdelraouf, Kamilia, Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192146/
https://ncbi.nlm.nih.gov/pubmed/27799200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01957-16
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