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Assessment of the In Vivo Efficacy of WCK 5222 (Cefepime-Zidebactam) against Carbapenem-Resistant Acinetobacter baumannii in the Neutropenic Murine Lung Infection Model

We evaluated the in vivo efficacy of human-simulated WCK 5222 (cefepime-zidebactam) against cefepime-resistant Acinetobacter baumannii strains (n = 13) in the neutropenic murine lung infection model. Twelve isolates were meropenem resistant. In control animals and those that received cefepime or zid...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Avery, Lindsay M., Abdelraouf, Kamilia, Nicolau, David P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201064/
https://ncbi.nlm.nih.gov/pubmed/30181365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00948-18
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