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Pharmacokinetic/Pharmacodynamic Modeling and Simulation of Cefiderocol, a Parenteral Siderophore Cephalosporin, for Dose Adjustment Based on Renal Function

Cefiderocol, a novel parenteral siderophore cephalosporin, exhibits potent efficacy against most Gram-negative bacteria, including carbapenem-resistant strains. Since cefiderocol is excreted primarily via the kidneys, this study was conducted to develop a population pharmacokinetics (PK) model to de...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Katsube, Takayuki, Wajima, Toshihiro, Ishibashi, Toru, Arjona Ferreira, Juan Camilo, Echols, Roger
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192099/
https://ncbi.nlm.nih.gov/pubmed/27795374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01381-16
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