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Nucleic acid delivery into skin for the treatment of skin disease: proofs-of-concept, potential impact, and remaining challenges

Nucleic acids (NAs) hold significant potential for the treatment of several diseases. Topical delivery of NAs for the treatment of skin diseases is especially advantageous since it bypasses the challenges associated with systemic administration which suffers from enzymatic degradation, systemic toxi...

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Bibliografiske detaljer
Udgivet i:J Control Release
Main Authors: Zakrewsky, Michael, Kumar, Sunny, Mitragotri, Samir
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192040/
https://ncbi.nlm.nih.gov/pubmed/26385169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.017
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