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Nucleic acid delivery into skin for the treatment of skin disease: proofs-of-concept, potential impact, and remaining challenges

Nucleic acids (NAs) hold significant potential for the treatment of several diseases. Topical delivery of NAs for the treatment of skin diseases is especially advantageous since it bypasses the challenges associated with systemic administration which suffers from enzymatic degradation, systemic toxi...

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Dettagli Bibliografici
Pubblicato in:J Control Release
Autori principali: Zakrewsky, Michael, Kumar, Sunny, Mitragotri, Samir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192040/
https://ncbi.nlm.nih.gov/pubmed/26385169
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.017
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