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Therapeutic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease

The high prevalence of skin diseases and their visible symptoms result in major physical, emotional, and economic burden for which few solutions exist. To address this unmet medical need, topical delivery of RNAi such as siRNA holds many advantages including direct access to the diseased site, poten...

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Dettagli Bibliografici
Pubblicato in:J Control Release
Autori principali: Zakrewsky, Michael, Mitragotri, Samir
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289309/
https://ncbi.nlm.nih.gov/pubmed/27612407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.09.003
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