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Therapeutic RNAi robed with ionic liquid moieties as a simple, scalable prodrug platform for treating skin disease

The high prevalence of skin diseases and their visible symptoms result in major physical, emotional, and economic burden for which few solutions exist. To address this unmet medical need, topical delivery of RNAi such as siRNA holds many advantages including direct access to the diseased site, poten...

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Detalhes bibliográficos
Publicado no:J Control Release
Main Authors: Zakrewsky, Michael, Mitragotri, Samir
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289309/
https://ncbi.nlm.nih.gov/pubmed/27612407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2016.09.003
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