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IRE1α inhibition by natural compound genipin on tumour associated macrophages reduces growth of hepatocellular carcinoma
Accumulating evidences postulated the influential roles of macrophages in mediating hepatocellular carcinoma (HCC) initiation and progression. In this study, we demonstrate that a small molecule, genipin reduced HCC growth through suppressing IRE1α-mediated infiltration and priming of tumour associa...
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| 出版年: | Oncotarget |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Impact Journals LLC
2016
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5190060/ https://ncbi.nlm.nih.gov/pubmed/27270308 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9696 |
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