Autophagy-induced RelB/p52 activation mediates tumour-associated macrophage repolarisation and suppression of hepatocellular carcinoma by natural compound baicalin

The plasticity of tumour-associated macrophages (TAMs) has implicated an influential role in hepatocellular carcinoma (HCC). Repolarisation of TAM towards M1 phenotype characterises an immune-competent microenvironment that favours tumour regression. To investigate the role and mechanism of TAM repo...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Tan, H-Y, Wang, N, Man, K, Tsao, S-W, Che, C-M, Feng, Y
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4632300/
https://ncbi.nlm.nih.gov/pubmed/26492375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.271
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