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Fluorescent probes reveal a minimal ligase recognition motif in the prokaryotic ubiquitin-like protein from Mycobac-terium tuberculosis
The prokaryotic ubiquitin-like protein (Pup) based proteasomal system in the pathogen Mycobacterium tuberculosis (Mtb) is essential for its survival in a mammalian host. The Pup ligase enzyme, PafA, conjugates Pup to a suite of proteins targeted for proteasomal degradation, and is necessary for pers...
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| Izdano u: | J Am Chem Soc |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5189686/ https://ncbi.nlm.nih.gov/pubmed/23402667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311376h |
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