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Fluorescent probes reveal a minimal ligase recognition motif in the prokaryotic ubiquitin-like protein from Mycobac-terium tuberculosis
The prokaryotic ubiquitin-like protein (Pup) based proteasomal system in the pathogen Mycobacterium tuberculosis (Mtb) is essential for its survival in a mammalian host. The Pup ligase enzyme, PafA, conjugates Pup to a suite of proteins targeted for proteasomal degradation, and is necessary for pers...
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| 出版年: | J Am Chem Soc |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2013
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5189686/ https://ncbi.nlm.nih.gov/pubmed/23402667 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja311376h |
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