Protein tyrosine phosphatase receptor-type O (PTPRO) exhibits characteristics of a candidate tumor suppressor in human lung cancer

Previous study in our laboratory demonstrated suppression of the gene for protein tyrosine phosphatase receptor-type O (PTPRO) in primary and established rat hepatomas. The present study showed methylation-mediated silencing of this gene in primary human lung tumors and in several human lung cancer...

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Bibliographic Details
Main Authors: Motiwala, Tasneem, Kutay, Huban, Ghoshal, Kalpana, Bai, Shoumei, Seimiya, Hiroyuki, Tsuruo, Takashi, Suster, Saul, Morrison, Carl, Jacob, Samson T.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2004
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC518843/
https://ncbi.nlm.nih.gov/pubmed/15356345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0405451101
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