Suppression of the protein tyrosine phosphatase receptor type O gene (PTPRO) by methylation in hepatocellular carcinomas

A diet lacking folic acid and choline and low in methionine (folate/methyl deficient diet, FMD diet) fed to rats is known to produce preneoplastic nodules (PNNs) after 36 weeks and hepatocellular carcinomas (tumors) after 54 weeks. FMD diet-induced tumors exhibit global hypomethylation and regional...

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Bibliografische gegevens
Hoofdauteurs: Motiwala, Tasneem, Ghoshal, Kalpana, Das, Anindita, Majumder, Sarmila, Weichenhan, Dieter, Wu, Yue-Zhong, Holman, Kristen, James, S Jill, Jacob, Samson T, Plass, Christoph
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2003
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3020652/
https://ncbi.nlm.nih.gov/pubmed/14508512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.onc.1206750
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