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Epigenetic regulation of protein tyrosine phosphatases: potential molecular targets for cancer therapy
Promoter methylation-mediated silencing is a hallmark of many established tumor suppressor genes. This review focuses on the methylation and suppression of a receptor-type tyrosine phosphatase gene, PTPRO, in a variety of solid and liquid tumors. In addition, PTPRO exhibits many other characteristic...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2005
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3028596/ https://ncbi.nlm.nih.gov/pubmed/15803146 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.cgt.7700828 |
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