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The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target

p53 is a sequence-specific short-lived transcription factor expressed at low concentrations in various tissues while it is upregulated in damaged, tumoral or inflamed tissue. In normally proliferating cells, p53 protein levels and function are tightly controlled by main regulators, i.e., MDM2 (mouse...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Int J Mol Sci
Egile Nagusiak: Fierabracci, Alessandra, Pellegrino, Marsha
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI 2016
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187775/
https://ncbi.nlm.nih.gov/pubmed/27897991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17121975
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