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The Double Role of p53 in Cancer and Autoimmunity and Its Potential as Therapeutic Target

p53 is a sequence-specific short-lived transcription factor expressed at low concentrations in various tissues while it is upregulated in damaged, tumoral or inflamed tissue. In normally proliferating cells, p53 protein levels and function are tightly controlled by main regulators, i.e., MDM2 (mouse...

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Bibliografski detalji
Izdano u:Int J Mol Sci
Glavni autori: Fierabracci, Alessandra, Pellegrino, Marsha
Format: Artigo
Jezik:Inglês
Izdano: MDPI 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5187775/
https://ncbi.nlm.nih.gov/pubmed/27897991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms17121975
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