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p53 Abnormalities and Potential Therapeutic Targeting in Multiple Myeloma

p53 abnormalities are regarded as an independent prognostic marker in multiple myeloma. Patients harbouring this genetic anomaly are commonly resistant to standard therapy. Thus, various p53 reactivating agents have been developed in order to restore its tumour suppressive abilities. Small molecular...

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Detalhes bibliográficos
Main Authors: Teoh, P. J., Chng, W. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4083709/
https://ncbi.nlm.nih.gov/pubmed/25028664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/717919
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