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p53 Abnormalities and Potential Therapeutic Targeting in Multiple Myeloma
p53 abnormalities are regarded as an independent prognostic marker in multiple myeloma. Patients harbouring this genetic anomaly are commonly resistant to standard therapy. Thus, various p53 reactivating agents have been developed in order to restore its tumour suppressive abilities. Small molecular...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4083709/ https://ncbi.nlm.nih.gov/pubmed/25028664 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/717919 |
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